PIM447 (LGH447) Corner Notch

PIM447 (LGH447) Corner NotchPIM447 is a novel pan PIM kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3?, PKN1, and PKC?, but at a significantly lower potency with IC50 between 1 and 5 ? M (>105 fold differential relative to the Ki on PIMs).

Corning Polypropylene Cryogenic Vial Rack

KDR and CSF-1R with IC50 of 80 nM

inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway and induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a dose-dependent manner

Corning 150mL Vacuum Filter/Storage Bottle System

Aprotinin is a small protein serine protease inhibitor (Kd=0

irreversible inhibition of ornithine decarboxylase (ODC)

Latamoxef sodium is an antibiotic and has anti-bacterial and anti-inflammation effects

g/ml and 4

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and increases capillary endothelial resistance as and platelet adhesion

a broad-spectrum penicillin antibiotic

also known as (-)-Tetramisole