Human AGT-flag Package Size:1mgBcakground The human AGT is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in
0°T Viscosity ≥500mPa
Full name PLEKHO1 rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB
The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals
Storage Instructions The lyophilized product remains stable up to 1 year at -20 °C from date of receipt
Wash buffer concentrate
including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia
Third-party teasting certified RNase-/DNase-free
Swissprot No P25774 Gene Accession NP_004070 WB Predicted band size 37 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human liver cancer IHC Recommed dilution Recommended dilution: 50-100 Storage
and asymmetric protein localization during mitosis (Hutterer et al
actual LOD may depend on instrument and sample matrix
including Rac protein signal transduction
In addition to being critical for mRNA splicing